KRAMERIA LAPPACEA PDF
Krameria lappacea (Rhatany or Ratanhia, Krameriaceae) is an endangered, overexploited medicinal plant from the semi-deserts of Andean. Description and images of Krameria lappacea (), a native Chilean plant, provided by the supplier of native exotic Chilean seeds and organizer of plant watching. Krameria lappacea (Rhatany or Ratanhia, Krameriaceae) is an endangered, overexploited medicinal plant from the semi-deserts of Andean South America, and.
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Kottas-Heldenberg and Sohn Vienna, Austria. In a previous study we could show that not only tannins with their astringent and antimicrobial properties, but also the neglected compound class of lignan derivatives with their pronounced anti-inflammatory activities play an lappacsa role in the use of the herbal drug against inflammatory disorders of mouth and throat.
Standards Compounds 1 — 6and 8 — 12 were isolated and their structures elucidated in a previous study . The detector signal was linear in the tested range with a correlation coefficient higher than 0. Integrated Taxonomic Lapapcea System.
When finely powdered, the dried roots furnished a frequent constituent of tooth powders. Highest deviations within the root samples were found for compounds 5 and 12 with contents ranging from 0. This issue could be explained by the shorter maceration time 3 dayssince regular Tinctura Ratanhiae is prepared by a double maceration over a period of two weeks. The topical anti-inflammatory properties of the secondary metabolites were comparable to the drug indomethacin ID 50 lappaceaa 0.
Open laopacea a separate window. Thus, the HPLC-method, developed in the present study, is a significant improvement and innovation, since it enables for the first time the quantitative analysis of lignan derivatives in Ratanhiae radix as well as in Tinctura Ratanhiae.
Wikimedia Commons has media related to Krameria. Compounds 1 — 6and 8 — 12 were isolated and their structures elucidated in a previous study .
HPLC—MS experiments in positive and negative electrospray kgameria mode confirmed identity and peak purity of analytes. Wikispecies has information related krameeia Krameria. Neue lipophile Benzofuranderivate aus Ratanhiawurzel.
Chromatograms of the standard mix, a typical root and a tincture sample under optimized conditions are depicted in Fig. These pharmacological findings make a quality assessment of Ratanhiae radix and its preparations with an adequate analytical method with focus on the class of lignan derivatives, necessary.
Calibration and validation Individual stock solutions of standard compounds were prepared in methanol. Stuppner, Lignan derivatives from Krameria lappacea roots inhibit acute inflammation in vivo and pro-inflammatory mediators in vitro, J Nat Prod. Maximum deviations within one day intra-day precision were 4.
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ESI, alternating mode; spray voltage: Views Read Edit View history. United States Department of Agriculture.
The drug was introduced into European medicine over years ago as a remedy against stomach aches, diarrhoea, menstrual problems, nose bleeds and oropharyngeal inflammation [2,3]. All other parameters were maintained.
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The developed HPLC method enables the quantification of twelve active lignan derivatives in the roots, and is also suitable for the determination of the constituents in Tinctura Ratanhiae. The powdered roots have also served, especially in Portugalto color wines ruby red. The therapeutic indications comprise mild inflammations of mouth and throat krakeria as stomatitis, gingivitis and pharyngitis .
Besides already known antimicrobial, antioxidant, and photoprotective properties [3,5,7,9] of root extracts, we could demonstrate in a previous study the pronounced anti-inflammatory activity of a dichloromethane extract as well as of 11 isolated lignan derivatives compounds 1 — 6 and 8 — Journal of Pharmaceutical and Biomedical Analysis.
Repeatability of the method was assured by relative standard deviations of multiple injections. None of the compounds 1 — 12 could be quantified since their content was below the LOQ and even below the LOD, indicating an exhaustive extraction. Only for compound 4 LOD The composition of the mobile phase consisted of 0. For quantification of compound 8 and 11 the obtained solutions were further diluted with methanol 1: One prominent constituent of the investigated extracts 3-formyl 4-hydroxyphenyl E -propenylbenzofuran; compound 7an additional lignan derivative, was isolated in course of the present study.
Optimal results were obtained by applying the tincture samples directly on top of a polyamide column followed by elution with methanol.
The content of the lignan derivatives in the tincture samples 2—4 was very consistent with the highest variation for compound 7 0. Several mixtures thereof Results and discussion 3. For an exhaustive extraction the procedure was carried out twice. In order to present the results in a clear form the extracted ion chromatograms EIC were selected for presentation see Fig. Rhatany is also the name given to krameria roota botanical remedy consisting of the dried root of para rhatany Krameria argentea or Peruvian rhatany Krameria lappacea.
The root bark contains an almost insoluble free red substance called ratanhia red.
Krameria lappacea Images – Useful Tropical Plants
From Wikipedia, the free encyclopedia. National Center for Biotechnology InformationU. Germplasm Resources Information Network. Isolation of ratanhine, a new dineolignan from the medicinal Ratanhiae Radix. The quality of those complied with the Austrian Pharmacopoeia.
This page was last edited on 21 Novemberat Conclusions In a previous study we could show that not only tannins with their astringent and antimicrobial properties, but also the neglected compound class of lignan derivatives with their pronounced anti-inflammatory activities play an important role in the use of the herbal kramerria against inflammatory disorders of mouth and throat.