PDF | Phytochemical studies on the aerial parts of Prangos uloptera, an endemic Iranian species of the genus Prangos, yielded five coumarins. Keywords: Prangos uloptera, Apiaceae, Umbelliferae, coumarin, Umbelliferae) is an endemic Iranian species of the genus Prangos that comprises ca. Antimicrobial and antioxidant activities of coumarins from the roots of Ferulago campestris (Apiaceae). Basile A(1), Sorbo S, Spadaro V, Bruno.

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Progress in study of chemical constituents and anti-tumor activities of Cnidium monnieri.

Foeniculum extracts are noted to reduce allergic inflammation as well as posess an analgesic effect. Osthole is noted to reduce interleukin-1 providing anti-inflammatory activity that may be an alternative to steroidal medications in some situations.

However, livestock who graze on large amounts of spoiled Yellow clover, Melilotus officianlis, or Sweet Vernal Grass, Anthoxanthum odoratum ARE reported to suffer hematologic and bleeding disorders which can be fatal when a large amount is ingested, due to the conversion of coumarin to dicoumarol, a potent anticoagulant.

A similar investigation on vitiligo used an encapsulated form of khellin with L-phenylalanine and phosphatidylcholine in comibination with UVA and compared this with the results of the use of UV alone.

Coumarins from the aerial parts of Prangos uloptera (Apiaceae)

Many antiviral compounds from plants are noted to be photosensitizers. Lomatium and a similar Apiacie family member Ligusticum both contain the coumarin relative ligustilide and the essential oil Apiol, both credited with antimicrobial activity.

Int J Low Extrem Wounds. The plants do not become woody or highly mineralized.

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Studies have shown Angelica to increase the use of glucose or sugar in uterine cells, and to promote the synthesis of DNA in the uterus and ovaries.


Some of the members of this coumsrin considered “herbs” produce scents that are believed to Coumarins from umbels of Prangos pabularia Lind. The furnaochromones may have a positive activity on the vascular system through a variety of mechanisms. Views Read Edit View history. Psoralen and related comounds may be photosensitizing to bacteria and viruses, and plants containing these photosensitizers may be antimicrobial via a mechanim of phototoxiticy involving DNA disruption in the microbes.

THE APIACEAE FAMILY – Medicinal Plant Research Summary

Comparative screening of plant essential oils: Coumarins and related compounds may have anti tumor effects via a photo phenomenon.

Therefore anticoagulant action from dried plant material such as Melilotus officianalis or Trifolium pratense is theoretically possible but not emphasized in historic or modern literature on coumarins except in the case of accidental poisoning of livestock.

Osthole promoted alkaline phosphatase levels levels and osteoblast activity and proliferation as well as inhibited bone resorption by reducing activity and maturation of osteoclasts. Observation on ffrom results of treatment of female infertility in cases. Outwardly, the plants are not highly aromatic, but crushing or chewing the leaves coumsrin seeds will release the volatile oils and thereby the aromas. Antibacterial activity of components from Lomatium californicum. Another possibilityis enhanced digestion of interstitial proteins by macrophages.

Apiaceae – Wikipedia

The phototoxicity of 8-methoxythionepsoralen and 6-methylthionecoumarin. Activity against drug resistant-tuberculosis strains of plants used in Mexican traditional medicine to treat tuberculosis and other respiratory diseases.

Khim Prir Soedin 6: Animal studies on a coumarin containing Melilotus officinalis was shown to apiaxeae acute vascular inflammation. Centella asiatica Indena S. Umbelliferone has been shown to have a normalizing effect on collagen, a mechanism presumed to help protect the kidneys and nerves from the contributions of excessive collagen deposition in nephropathy and neuropathy.


The mechanism underlying the hypocholesterolaemic activity of aqueous celery extract, its butanol and aqueous fractions in genetically hypercholesterolaemic RICO rats. Osthole increases glycosylation of hepatitis B surface antigen and suppresses the secretion of hepatitis B virus in vitro. Angelica has been found to have an anhistamine and antiserotinin effect which may be an explanation of the reported anti-allergy effects.

Iten F, Saller R. Apium graveolans is also noted to have numerous anti-inflammatory effects in the blood. Furthermore, the dose that accomplishes antithrombotic activity showed no pro-hemorrhage activity, and displays a protective effect from ethanol induced gastric ulcers.

Photophysical properties and photobiological activity of the furanochromones visnagin and khellin. The seeds have an oily endosperm [5] [6] and often contain essential oils, containing aromatic compounds that are responsible for the flavour of commercially important umbelliferous seed such as anisecumin and coriander.

Plant photosensitizers with antiviral properties. Modulation of mitogen-activated protein kinases by 6-nitrohydroxycoumarin mediates apoptosis in renal carcinoma cells. Collagen repair and regeneration also becomes aberrant in diabetes with total collagen increasing but soluable and transportable types of collagen decreasing. Psoralen, angelicin and khellin have all been shown to exibit an inhibitory effect on cyclic AMP phosphodiesterase.

Osthole can reduce the frequency of action potential in neurons via inhibition of calcium channels.

Centella has been used traditionally as something of panacea for general strength and longeveity. The seeds may be used in cuisine, as with coriander Coriandrum sativumfennel Foeniculum vulgarecumin Cuminum cyminumand caraway Carum carvi.

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