Boesenbergia pandurata (Roxb.) Schltr. is a tropical plant that has been used as a spice and in traditional medicine. B. pandurata contains various bioactive. This plant has 8 different botanical names which are Boesenbergia cochinchinensis (Gagnep.) Loes., Boesenbergia pandurata (Roxb.) Schltr. The medicinal plant, Boesenbergia pandurata (Roxb.) Schltr., has been reported to possess anti-oxidative and anti-inflammatory properties;.

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In all treatments, roots spontaneously grew after 10—14 days. Bioactive compounds that were extracted from the leaves, stems, and rhizomes of B. These two factors play a pivotal role in skin hydration and barrier function 34. Candidal Adhesion Inhibitor Candidal pandurzta is an essential mechanism for Candida species to adhere to the oral surfaces to colonise the mouth and cause oral diseases. Activity of panduratin A isolated from Kaempferia pandurata Roxb.

B The protein expression of matriptase, boesenbetgia, filaggrin, and caspase in panduratin A treated HaCaT cells.

Boesenbergia rotunda – Wikipedia

The following year, Yanti et al. Piantadosi C, Skulason VG. An acidic pH is essential for the antimicrobial effect and enzymatic activity, contributing to ceramide metabolism 12 The use of local medicinal plants to treat this disease is popular due in part to its safety, ease of access and availability at low cost. The leaf sheaths are red, the blades are oval shape and the apex of leaves are sharp.

Potential activity of ethanolic extract of Boesenbergia rotunda L. Its extracts in other studies show that it inhibits the growth of fungi responsible for oral thrush and candidiasis most commonly observed as an infection in patients who have HIV. Pretreatment of the dentures pandurtaa B.

Journal of Oral Science.

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With the development of medicinal chemistry and bioinformatics, we are well on our way to successfully develop plant-based drugs. Chemoenzymatic synthesis of enantiomerically enriched kavalactones. B Cytotoxicity of panduratin A.


Optimization of the culture conditions for B. In vitro culture provides an immediate source of compounds in a sustainable approach and as study subjects for molecular biology, crop improvements, and genetics studies. Isoflavonoid production by soy plant callus suspension culture.

This species belongs to the family of Zingiberaceae. Journal of Pharmacology and Toxicology. Among these proteins, filaggrin is an important protein because NMF is produced by the degradation of filaggrin.

Amplification consisted of more than 22 cycles: Its leaves are used by locals to alleviate food allergic and poisoning.

Traditional Recipes For Health and Harmony. Chuakul W, Boonpleng A. Several studies showed that peroxisome proliferator-activated receptors PPARsa family boesejbergia nuclear hormone receptors, are closely associated with epidermal homeostasis.

Pathogenic and Spoilage Bacteria Inhibition Activities Pathogenic bacteria are a group of bacteria that induce diseases in humans and plants. Am J Infect Control. It was found that substitutions at positions 4 and 5 gave the lowest and closest energies to the reference compounds from the calculated complexation energies, and new ligands were designed by substituting various functional groups on these positions.

Boesenberfia, cardamonin, panduratin A, and hydroxypanduratin A are potential drug targets to inhibit HIV-1 protease activity. Table 2 Inhibitory activities exhibited by B. It is normally cultivated at small home ranches and used as a condiment in food such as curry and soup due to its aromatic flavour, which promotes appetite.

Whole plant of B. Bound antibodies were detected with a horse-radish peroxidase-conjugated secondary antibody 1: Uptake into mouse brain of four compounds present in the psychoactive beverage kava. Various synthetic routes to racemic and enantiopure kavalactones have been studied via Aldol reaction involving cinnamaldehydes but none of them are generally applicable to the synthesis of oxygen-substituted kavalactones such as yangonin [ — ].

Effects of biotic and abiotic elicitors on cell growth and tanshinone accumulation in Salvia miltiorrhiza cell cultures. Singh YN, Blumentahl M. In vitro study of antiviral activity of plant crude-extracts against the foot and mouth disease virus. Suppressive effect of ethanolic Kaempferia pandurata Roxb. Boesenbergia rotunda is a herb from the Boesenbergia genera under the Zingiberaceae family.


Boesenbergia rotunda: From Ethnomedicine to Drug Discovery

Although the effect of these plant extracts paled in comparison to metronidazole, a commercial antibiotic with an IC 50 value of 0. Rao and Ravishankar [ 76 ] described a nonredundant list of plant-derived pharmaceuticals and highlighted the importance of the availability of contaminant-free samples, optimum multiplication, and regeneration protocol for metabolite engineering studies. Mucin-mixed panduratin A at concentrations between 0.

With that, uniform quality and yield of the compounds could be achieved without problem with variation due to seasonal and geographical reason [ 76 ]. The above ground part is composed of leaf stalk that has a leaf sheath covering it.

These findings suggest that panduratin A could be a potential therapeutic agent against prostate cancer. These results demonstrate that BPE and panduratin A stimulate the formation of both filaggrin and NMF by elevating profilaggrin processing enzymes and caspase Thus, the mRNA and protein levels of keratinocyte differentiation markers, such as loricrin, in-volucrin, and transglutaminase were investigated to clarify the ability of BPE and panduratin A to form CE.

Therefore, these plant extracts can be used to potentially treat PAF-mediated diseases. Synthesis of some alpha,beta-unsaturated beta, delta-disubstituted. Further studies of flavonoids of the black rhizomes Boesenbergia pandurata. In a separate study, Tewtrakul and colleagues [ 26 ] investigated the anti-HIV protease activity of chloroform, methanol and water extracts of several traditional herbs used by Thai locals as self-medication for AIDS.

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